Single cell transcriptomics of the cerebral cortex of mice lacking the PRC2 gene eed
Abstract Objective The Polycomb Repressive Complex 2 (PRC2) regulates neural stem cell behaviour during development of the cerebral cortex, yet how the loss of PRC2 developmentally influences cell identity in the mature brain is poorly defined.Using a mouse model in which the PRC2 gene Embryonic ectoderm development (Eed) was conditionally deleted